MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene, investigated for its role in AMPK signaling, metabolic homeostasis and exercise physiology.
Reported to activate AMPK, influencing glucose metabolism and mitochondrial function in vitro.
Emerging preclinical studies in exercise physiology and aging research.
- Exercise physiology and endurance research
- Metabolic health and insulin-sensitivity studies
- Ageing and cellular-decline investigation
PeriodDoseUnits (U-100)
Research protocol5–10 mg—
Adjust dose based on study design and tolerability. Consult your protocol.
For research use only. Not for human or veterinary consumption. Not FDA-approved for the treatment or prevention of any disease.

