Overview
MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene, investigated for its role in AMPK signaling, metabolic homeostasis and exercise physiology.
Mechanism of action
Reported to activate AMPK, influencing glucose metabolism and mitochondrial function in vitro.
Research summary
Emerging preclinical studies in exercise physiology and aging research.
Research applications
- Exercise physiology and endurance research
- Metabolic health and insulin-sensitivity studies
- Ageing and cellular-decline investigation
Typical research dosing
| Period | Dose | Units (U-100) |
|---|---|---|
| Research protocol | 5–10 mg | — |
Reconstitution & storage
Reconstitute with 3 mL bacteriostatic water for 10 mg vial.
Safety
Research use only.
References
- Lee C. et al. Cell Metabolism 2015;21:443-454
For research use only. Not for human or veterinary consumption. Not FDA-approved for the treatment or prevention of any disease.